Quinolines and derivatives
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Filtered Search Results
Medchemexpress LLC Lobeglitazone (sulfate) | 763108-62-9 | MFCD28502044 | 99.6% | 578.61 g·mol⁻¹ | C24H26N4O9S2 | 10 MG
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Lobeglitazone sulfate is a thiazolidinedione-class small molecule used for research as a peroxisome proliferator-activated receptor (PPAR) agonist. It has reported activity on PPARγ (EC50 ≈ 137.4 nM) and PPARα (EC50 ≈ 546.3 nM) and is applied in preclinical studies of metabolic, inflammatory, fibrotic, and atherosclerotic pathways. Follow the product SDS for handling and storage instructions.
- Acts as a PPARγ and PPARα agonist with published EC50 values.
- Supports studies of anti-diabetic, anti-inflammatory, and anti-fibrotic mechanisms.
- High purity suitable for biochemical and cellular assays.
- Provided as a sulfate salt to aid solubility in experimental media.
- Stable under recommended storage; consult SDS for solvent storage conditions.
- Supplied in small quantities appropriate for research workflows.
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Medchemexpress LLC Quin C1 | 786706-21-6 | 98.5% | 445.51 | 25 MG
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Quin C1 is a highly specific and potent agonist for formyl peptide receptor 2 (FPR2/ALX). Quin-C1 significantly reduces the neutrophil and lymphocyte counts in BALF, diminishes expression of TNF-α, IL-1β, KC, and TGF-β1, and decreases collagen deposition in lung tissue. Quin C1 has the potential for the research of lung injury.
- Highly specific and potent agonist for formyl peptide receptor 2 (FPR2/ALX).
- Significantly reduces neutrophil and lymphocyte counts in BALF.
- Diminishes expression of TNF-α, IL-1β, KC, and TGF-β1.
- Decreases collagen deposition in lung tissue.
- Potential for research of lung injury.
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Medchemexpress LLC CP 339818 (hydrochloride) | 478341-55-8 | 99.6% | 340.89 | 25 MG
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CP 339818 hydrochloride is a non-peptide blocker for Kv1.3 and Kv1.4 channels. It also inhibits HCN channels and exhibits significantly weaker blocking effects on several other Kv channels. This compound selectively blocks Kv1.3, thereby inhibiting the activation process of human T cells, and is useful for studying the physiological functions of HCN and Kv channels.
- Kv1.3 channel blocker (IC50 = 200 nM).
- Kv1.4 channel blocker.
- Inhibits HCN channels (HCN1 and HCN4).
- Selectively inhibits human T cell activation.
- Suitable for studying physiological functions of HCN and Kv channels.
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Medchemexpress LLC Imiquimod (hydrochloride) | 99011-78-6 | 10 MM 1 ML
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Imiquimod hydrochloride, also known as R 837 hydrochloride, is an immune response modifier and a selective toll-like receptor 7 (TLR7) agonist. This compound exhibits antiviral and antitumor effects in vivo, making it valuable for various research applications.
- Used for research of external genital, perianal warts, cancer, and COVID-19
- Can induce psoriasis models
- Exhibits antiviral effects in vivo
- Exhibits antitumor effects in vivo
- Acts as a selective toll-like receptor 7 (TLR7) agonist
- Functions as an immune response modifier
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Selleck Chemical LLC RESIQUIMOD R-848-1G
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NC3234759 RESIQUIMOD R-848-1G
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TARGETMOL CHEMICALS INC PD158780 10MG
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Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PD 158780 reversibly inhibits auto and transphosphorylation of all four members of the ErbB receptor superfamily EGFR ErbB2 ErbB3 and ErbB4 (IC50s 8uM 49 nM 52 nM and 52 nM in cell assay). purity: 99%
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Medchemexpress LLC Pomalidomide-amido-c5-peg2-c6-chlorine | 1835705-69-5 | 98.75% | 594.10 | 25 MG
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Pomalidomide-amido-C5-PEG2-C6-chlorine is a derivative of Pomalidomide. It is intended for research use only and is not sold to patients. The compound has a molecular weight of 594.10 and a chemical formula of C29H40ClN3O8. It appears as a white to off-white solid. This compound is cited in research related to the modular design of PROTACs for the degradation of oncogenic BCR-ABL.
- It is a derivative of Pomalidomide.
- It is used for research purposes only.
- It is a solid with a white to off-white appearance.
- It has been utilized in studies concerning PROTAC design for degrading oncogenic BCR-ABL.
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eMolecules 2105938-35-8 | N2,N6-Dicyanopyridine-2,6-bis(carboximidamide) | Ambeed213.204 | C9H7N7 | 97.000 | N=C(NC#N)c1cccc(n1)C(=N)NC#N | 1g | 845535526
N2,N6-Dicyanopyridine-2,6-bis(carboximidamide) | Ambeed | 2105938-35-8213.204 | C9H7N7 | 97.000 | N=C(NC#N)c1cccc(n1)C(=N)NC#N | 1g | 845535526
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Sigma Aldrich Fine Chemicals Biosciences Ciprofloxacin hydrochloride European Pharmacopoeia (EP) Reference Standard | 86393-32-0 | MFCD00242856 |
Ciprofloxacin hydrochloride European Pharmacopoeia (EP) Reference Standard | Mol Wt: 385.82 | 86393-32-0 | MFCD00242856 |
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eMolecules 1128-61-6 | 6-FLUORO-2-METHYLQUINOLINE | AstaTech | MFCD00041233 | 161.179 | C10H8FN | 97.000 | Cc1ccc2cc(F)ccc2n1 | 5g | 392632903
6-FLUORO-2-METHYLQUINOLINE | AstaTech | 1128-61-6 | MFCD00041233 | 161.179 | C10H8FN | 97.000 | Cc1ccc2cc(F)ccc2n1 | 5g | 392632903
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Ambeed AMBEED
5000848564 2 2-DIMETHOXY-7-AZASPIR 250MG
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Medchemexpress LLC Recombinant mouse interleukin-31 | >85.0% | 2 UG
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Recombinant mouse interleukin-31 produced in HEK293 cells and supplied as a filtered PBS solution for research applications. The protein is provided as a solution (2 μg vial) with a C-terminal His tag and is characterized by predicted mass and receptor-binding activity suitable for in vitro assays.
- Expressed in HEK293 mammalian cells for native folding and glycosylation.
- C-terminal His tag facilitates purification and detection.
- Predicted molecular mass approximately 17.1 kDa.
- Purity greater than 85% as determined by reducing SDS-PAGE.
- Demonstrated receptor binding activity (ED50 reported in functional assay).
- Supplied in PBS, pH 7.4; store at -80°C and avoid repeated freeze-thaw cycles.
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Ambeed 7Bromo1 2dihydroisoquinolin3 4
7-Bromo-1,2-dihydroisoquinolin-3(4H)-one, 943751-93-7, 95%
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eMolecules 219763-82-3 | 4-Hydroxyquinoline-6-carbonitrile | Apollo Scientific | MFCD08063203 | 170.171 | C10H6N2O | 96.000 | Oc1ccnc2ccc(cc12)C#N | 1g | 562462240
4-Hydroxyquinoline-6-carbonitrile | Apollo Scientific | 219763-82-3 | MFCD08063203 | 170.171 | C10H6N2O | 96.000 | Oc1ccnc2ccc(cc12)C#N | 1g | 562462240
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Chemscene CHEMSCENE
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5000579432 HYDROQUINIDINE 25G
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